*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YQ8665000
CHEMICAL NAME           : Uracil, 1-allyl-6-amino-3-ethyl-
CAS REGISTRY NUMBER     : 642-44-4
BEILSTEIN REFERENCE NO. : 0175533
REFERENCE               : 4-25-00-04113 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H13-N3-O2
MOLECULAR WEIGHT        : 195.25
WISWESSER LINE NOTATION : T6NVNVJ A2U1 C2 FZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alacil
   * Allacyl
   * 1-Allyl-6-amino-3-ethyl-2,4(1H,3H)-pyrimidinedione
   * 1-Allyl-6-amino-3-ethyluracil
   * 1-Allyl-3-ethyl-6-aminotetrahydropyrimidinedione
   * 1-Allyl-3-ethyl-6-amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione
   * 6-Amino-3-ethyl-1-(2-propenyl)-2,4(1H,3H-)-pyrimidinedione
   * Aminometradine
   * Aminometramide
   * Catapyrin
   * 1-Ethyl-3-allyl-6-aminouracil
   * Katapyrin
   * Mictine
   * Mincard
   * S.C. 3497
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 14,392,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PRPHA8 Produits Pharmaceutiques.  (Paris, France)  V.1-16, 1946-61.  For
   publisher information, see PPRPAS.  Volume(issue)/page/year: 13,125,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PRPHA8 Produits Pharmaceutiques.  (Paris, France)  V.1-16, 1946-61.  For
   publisher information, see PPRPAS.  Volume(issue)/page/year: 13,125,1958
 
                            *** END OF RECORD ***