*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YQ8800000
CHEMICAL NAME           : Uracil, 6-amino-3-methyl-1-(2-methylallyl)-
CAS REGISTRY NUMBER     : 550-28-7
BEILSTEIN REFERENCE NO. : 0182347
REFERENCE               : 5-25-15-00393 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H13-N3-O2
MOLECULAR WEIGHT        : 195.25
WISWESSER LINE NOTATION : T6NVNVJ A1Y1&U1 C1 FZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aminoisometradin
   * Aminoisometradine
   * 6-Amino-1-metallyl-3-methylpyrimidine-2,4-dione
   * 6-Amino-3-methyl-1-(2-methylallyl)-2,4(1H,3H)-pyrimidinedione
   * 6-Amino-3-methyl-1-(2-methylallyl)uracil
   * 6-Amino-3-methyl-1-(2-methyl-2-propenyl)-2,4(1H,3H)-pyrimidinedione
   * Amisometradin
   * Amisometradine
   * 1-Methallyl-3-methyl-6-aminotetrahydropyrimidinedione
   * Rolicton
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 126,400,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 515 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 126,400,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 610 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,79,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 415 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,79,1989
 
                            *** END OF RECORD ***