*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YR0430000
CHEMICAL NAME           : Uracil, 5-fluoro-3-phthalidyl-
CAS REGISTRY NUMBER     : 82023-29-8
BEILSTEIN REFERENCE NO. : 5586734
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H7-F-N2-O4
MOLECULAR WEIGHT        : 262.21
WISWESSER LINE NOTATION : T56 BVO DHJ D- CT6MVNVJ EF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-2,4(1H,3H)-pyrimidinedi
     one
   * 5-Fluoro-3-phthalidyl-uracil
   * 3-Pfu
   * N(sub 3)-Phthalidyl-5-fluorouracil
   * 2,4(1H,3H)-Pyrimidinedione,  
   3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,1219,1982
 
                            *** END OF RECORD ***