*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YR0515000
CHEMICAL NAME           : Uracil, 5-(hydroxymethyl)-6-methyl-
CAS REGISTRY NUMBER     : 147-61-5
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H8-N2-O3
MOLECULAR WEIGHT        : 156.16
WISWESSER LINE NOTATION : T6MVMVJ E1Q F1
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 5-(Hydroxymethyl)-6-methyl-2,4(1H,3H)-pyrimidinedione
   * 5-Hydroxymethyl-4-methyluracil
   * 5-Hydroxymethyl-6-methyluracil
   * 4-Methyl-5-hydroxymethyluracil
   * 4-Methyl-5-oxymethyluracil
   * Pentoksil
   * Pentoxil
   * Pentoxyl
   * 2,4(1H,3H)-Pyrimidinedione, 5-(hydroxymethyl)-6-methyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 51,100,1988
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   AAGEAA Arkhiv Anatomii, Gistologii i Embriologii.  Archives of Anatomy,
   Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-101, 1916-91.  Discontinued  Volume(issue)/page/year: 65(11),19,1973
 
                            *** END OF RECORD ***