*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : YM3770000 CHEMICAL NAME : 1-alpha-4,5-alpha-H-Tropanium, 3-alpha-hydroxy-8-(p-phenylphenacyl)-, bromide, (-)-tropate CAS REGISTRY NUMBER : 5868-06-4 LAST UPDATED : 199103 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C31-H34-N-O4.Br MOLECULAR WEIGHT : 564.57 WISWESSER LINE NOTATION : T56 A AKTJ A1VR DR&& A1 GOVYR&1Q &E -(-)TROPATE COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * FA 402 * Fentonium bromide * 3-alpha-Hydroxy-8-(p-phenylphenacyl)-1-alpha-H,5-alpha-H-tropanium bromide (-)-tropate * Ketoscilium * Phentonium bromide * N-(4-Phenylphenacyl)-1-hyoscyaminium bromide * Ulcesium * Z 326 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 11600 ug/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - other changes REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3356682 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3356682 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3356682 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12100 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3356682 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - other changes REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3356682 *** END OF RECORD ***