*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : YR7350000 CHEMICAL NAME : Urea, 1-((p-acetylphenyl)sulfonyl)-3-cyclohexyl- CAS REGISTRY NUMBER : 968-81-0 BEILSTEIN REFERENCE NO. : 2225115 LAST UPDATED : 199806 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C15-H20-N2-O4-S MOLECULAR WEIGHT : 324.43 WISWESSER LINE NOTATION : L6TJ AMVMSWR DV1 COMPOUND DESCRIPTOR : Tumorigen Drug Reproductive Effector Human SYNONYMS/TRADE NAMES : * Acetohexamide * 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea * 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea * Benzenesulfonamide, 4-acetyl-N-((cyclohexylamino)carbonyl)- * Dimelin * Dimelor * Dymelor * Gamadiabet * Hypoglicil * Metaglucina * Minoral * NCI-C03247 * Ordimel * Tsiklamid * U 14812 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,34,1995 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,18,1982 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - woman DOSE : 900 mg/kg SEX/DURATION : female 26-39 week(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - stillbirth REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,187,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83998 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 627 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83998 No. of Facilities: 43 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1626 (estimated) No. of Female Employees: 833 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-50,78 *** END OF RECORD ***