*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YR8167500
CHEMICAL NAME           : Urea, 1-amidino-3-(p-((p-nitrophenyl)thio)phenyl)-
CAS REGISTRY NUMBER     : 20567-04-8
BEILSTEIN REFERENCE NO. : 2176303
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H13-N5-O3-S
MOLECULAR WEIGHT        : 331.38
WISWESSER LINE NOTATION : WNR DSR DMVMYZUM
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Amidino-3-(p-((p-nitrophenyl)thio)phenyl)urea
   * 3-Amidino-1-(p-((p-nitrophenyl)thio)phenyl)urea
   * T-1213
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 875 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 26,487,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,336,1969
 
                            *** END OF RECORD ***