*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS2585000
CHEMICAL NAME           : Urea, 1,1-bis(2-chloroethyl)-3-methyl-3-nitroso-
CAS REGISTRY NUMBER     : 69112-99-8
BEILSTEIN REFERENCE NO. : 2263769
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C6-H11-Cl2-N3-O2
MOLECULAR WEIGHT        : 228.10
WISWESSER LINE NOTATION : ONN1&VN2G2G
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1,1-Bis-(2-chloroethyl)-3-methyl-3-nitrosourea
   * 3-Nitroso-1,1-bis-(2-chloroethyl)-3-methylurea
   * Nitrosomethylbis(chloroethyl)urea
   * 1-Nitroso-1-methyl-3,3-bis-(2-chloroethyl)urea
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 76 mg/kg/6W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   JCROD7 Journal of Cancer Research and Clinical Oncology.  (Springer-Verlag
   New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.93-
   1979-  Volume(issue)/page/year: 94,131,1979
 
                            *** END OF RECORD ***