*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS4983250
CHEMICAL NAME           : Urea,
                          1-(2-chloroethyl)-3-(trans-2-hydroxycyclohexyl)-1-nit
                          roso-
CAS REGISTRY NUMBER     : 58494-43-2
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H16-Cl-N3-O4
MOLECULAR WEIGHT        : 265.73
WISWESSER LINE NOTATION : L6TJ AQ BMVNNO&2G -T
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * N-(2-Chloroethyl)-N'-(trans-2-hydroxycyclohexyl)-N-nitrosourea
   * 1-(2-Chloroethyl)-3-(trans-2-hydroxycyclohexyl)-1-nitrosourea
   * NSC 253947
   * trans-2-OH-CCNU
   * Urea, N-(2-chloroethyl)-N'-(2-hydroxycyclohexyl)-N-nitroso-, trans-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90140 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 65,149,1980
 
                            *** END OF RECORD ***