*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CL5603100 CHEMICAL NAME : 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 8-methyl-3-phenyl-, methyl ester, (exo,exo)- CAS REGISTRY NUMBER : 74163-84-1 LAST UPDATED : 198611 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C16-H21-N-O2 MOLECULAR WEIGHT : 259.38 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-beta-Methoxycarbonyl-3-beta-phenyltropane * (exo,exo)-8-Methyl-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester * Troparil * WIN 35065 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 48(1),15,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 48,26,1985 *** END OF RECORD ***