*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL5603370
CHEMICAL NAME           : 1-Azabicyclo(2.2.2)octane,
                          3-((2-chloro-6,11-dihydrodibenzo(b,e)thiepin-11-yl)ox
                          y)-, (Z)-2- butenedioate (1:1)
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H22-Cl-N-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 488.03
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(2-Chloro-6,11-dihydrodibenzo(b,e)thiepin-11-yloxy)quinuclidine maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 218 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 53,1806,1988
 
                            *** END OF RECORD ***