*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL8018000
CHEMICAL NAME           : 17a-Aza-D-homoandrostan-17-one,
                          3-(((4-(bis(2-chloroethyl)amino)phenyl)acetyl)oxy)-,
                          (3-beta,5-alpha)-
CAS REGISTRY NUMBER     : 43000-65-3
LAST UPDATED            : 199410
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C31-H44-Cl2-N2-O3
MOLECULAR WEIGHT        : 563.67
WISWESSER LINE NOTATION : E6 B666 FMVTJ A1 E1 POV1R DN2G2G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acetic acid, (4-(bis(2-chloroethyl)amino)phenyl)-,  
   17-oxo-D-homo-17a-azaandrostan-3-yl ester
   * ASE
   * Chlorambucil ester of  
   3-beta-hydroxy-13a-amino-13,17-seco-5a-androstan-17-oic-13,17-lactam
   * Homo-aza-steroidal ester of p-bis(2-chloroethyl)aminophenyl-acetic acid
   * N-S 90205
   * NSC 290205
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2500 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 175,165,1986
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 200 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 190,205,1987
 
TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 169 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 243,109,1990
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 25 ug/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5,279,1983
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 75 ug/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5,279,1983
 
                            *** END OF RECORD ***