*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM1980000
CHEMICAL NAME           : Azelaic acid
CAS REGISTRY NUMBER     : 123-99-9
BEILSTEIN REFERENCE NO. : 1101094
REFERENCE               : 4-02-00-02055 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C9-H16-O4
MOLECULAR WEIGHT        : 188.25
WISWESSER LINE NOTATION : QV7VQ
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Anchoic acid
   * Azelaic acid, technical grade
   * Emerox 1110
   * Emerox 1144
   * Heptanedicarboxylic acid
   * 1,7-Heptanedicarboxylic acid
   * Lepargylic acid
   * Nonanedioic acid
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   EMERY* Emery Industries, Inc., Data Sheets.  (4900 Este Ave., Cincinnati, OH
   45232)  Volume(issue)/page/year: S3B,-,1964
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3 mg
REACTION SEVERITY       : Mild
REFERENCE :
   EMERY* Emery Industries, Inc., Data Sheets.  (4900 Este Ave., Cincinnati, OH
   45232)  Volume(issue)/page/year: S3B,-,1964
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A067-313

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83495
       No. of Facilities: 170 (estimated)
       No. of Industries: 8
       No. of Occupations: 11
       No. of Employees: 1676 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83495
       No. of Facilities: 3427 (estimated)
       No. of Industries: 35
       No. of Occupations: 42
       No. of Employees: 34469 (estimated)
       No. of Female Employees: 7576 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NIOSH Analytical Method, 1994: Azelaic acid, 5019

 
                            *** END OF RECORD ***