*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM2000000
CHEMICAL NAME           : Azelaic acid, bis(2-ethylhexyl) ester
CAS REGISTRY NUMBER     : 103-24-2
BEILSTEIN REFERENCE NO. : 1806182
REFERENCE               : 3-02-00-01787 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C25-H48-O4
MOLECULAR WEIGHT        : 412.73
WISWESSER LINE NOTATION : 4Y2&1OV7VO1Y4&2
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Azelaic acid, di(2-ethylhexyl)ester
   * Bis(2-ethylhexyl)azelate
   * Bis-(2-ethylhexyl)ester kyseliny azelaove
   * Dioctyl azelate
   * Plastolein 9058
   * Plastolein 9058 DOZ
   * Staflex DOX
   * Truflex DOX
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 10 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8720 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1060 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MRLR** U.S. Army, Chemical Corps Medical Laboratories Research Reports.
   (Army Chemical Center, Edgewood Arsenal, MD)  Volume(issue)/page/year:
   #256,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MRLR** U.S. Army, Chemical Corps Medical Laboratories Research Reports.
   (Army Chemical Center, Edgewood Arsenal, MD)  Volume(issue)/page/year:
   #256,1954

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83279
       No. of Facilities: 713 (estimated)
       No. of Industries: 17
       No. of Occupations: 27
       No. of Employees: 12455 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83279
       No. of Facilities: 1084 (estimated)
       No. of Industries: 15
       No. of Occupations: 20
       No. of Employees: 17011 (estimated)
       No. of Female Employees: 3762 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***