*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM3930000
CHEMICAL NAME           : 2H-Azepin-2-one, hexahydro-7-isopropyl-4-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 31967-00-7
LAST UPDATED            : 199204
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H18-N-O.Cl-H
MOLECULAR WEIGHT        : 204.75
WISWESSER LINE NOTATION : T7MVTJ D1 GY1&1
SYNONYMS/TRADE NAMES :
   * Hexahydro-7-isopropyl-4-methyl-2H-azepin-2-one hydrochloride
   * 1-Isopropyl methylhexanone isoxime hydrochloride
   * Linksmenthonisoxim hydrochlorid
   * levo-Menthone isoxime hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 474 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 584 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 304 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - other changes
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
                            *** END OF RECORD ***