*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM3995000
CHEMICAL NAME           : 2H-Azepin-2-one, hexahydro-N-lauryl-
CAS REGISTRY NUMBER     : 59227-89-3
BEILSTEIN REFERENCE NO. : 0167211
REFERENCE               : 4-21-00-03206 (Beilstein Handbook Reference)
LAST UPDATED            : 199806
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C18-H35-N-O
MOLECULAR WEIGHT        : 281.54
WISWESSER LINE NOTATION : T7NVTJ A12
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Azone
   * 1-Dodecylazacycloheptan-2-one
   * 1-Dodecylhexahydro-2H-azepin-2-one
   * Laurocapram
   * N-Lauryl caprolactam
   * N 0252
   * Tranzone
   * USAF ND-72
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4882359
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DDIPD8 Drug Development and Industrial Pharmacy.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.3-    1977-  Volume(issue)/page/year:
   9,725,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DDIPD8 Drug Development and Industrial Pharmacy.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.3-    1977-  Volume(issue)/page/year:
   9,725,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4882359
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DDIPD8 Drug Development and Industrial Pharmacy.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.3-    1977-  Volume(issue)/page/year:
   9,725,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARDEAC Archives of Dermatology.  (AMA, 535 N. Dearborn St., Chicago, IL
   60610)  V.82-    1960-  Volume(issue)/page/year: 118,474,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DDIPD8 Drug Development and Industrial Pharmacy.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.3-    1977-  Volume(issue)/page/year:
   9,725,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DDIPD8 Drug Development and Industrial Pharmacy.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.3-    1977-  Volume(issue)/page/year:
   9,725,1983
 
                            *** END OF RECORD ***