*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM6160000
CHEMICAL NAME           : 1-Aziridineacetamide,
                          N,N'-(p-phenylenedimethylene)bis-
CAS REGISTRY NUMBER     : 10328-31-1
BEILSTEIN REFERENCE NO. : 1326686
REFERENCE               : 5-20-01-00052 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H22-N4-O2
MOLECULAR WEIGHT        : 302.42
WISWESSER LINE NOTATION : T3NTJ A1VM1R D1MV1- AT3NTJ
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Acetamide, N,N'-(p-xylylene)bis(2-(1-aziridinyl)-
   * N,N'-Bis-aziridinylacetyl-1,4-xylenediamine
   * N,N'-(p-Phenylenedimethylene)bis(1-aziridineacetamide)
   * N,N'-(p-Xylylene)bis(2-(1-aziridinyl)acetamide)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 25 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 24,924,1968
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2130 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 31,115,1975
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 940 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 31,115,1975
 
                            *** END OF RECORD ***