*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM6754000
CHEMICAL NAME           : 2-Aziridinecarboxamide,
                          1-(1-(2-cyano-1-aziridinyl)-1-methylethyl)-
CAS REGISTRY NUMBER     : 64118-86-1
BEILSTEIN REFERENCE NO. : 0476876
REFERENCE               : 5-22-01-00009 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H14-N4-O
MOLECULAR WEIGHT        : 194.27
WISWESSER LINE NOTATION : T3NTJ BVZ AX1&1&- AT3NTJ BCN
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Azimexon
   * Azimexona
   * Azimexone
   * BM-12,531
   * 2-(2-Cyanaziridinyl-(1))-2-(2-carbamoylaziridinyl-(1))propane
   * 1-(1-(2-Cyano-1-aziridinyl)-1-methylethyl)-2-aziridinecarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4370323
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4370323
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   5,174,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   34,333,1986
 
                            *** END OF RECORD ***