*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM6780000
CHEMICAL NAME           : 1-Aziridinecarboxamide, N-phenyl-
CAS REGISTRY NUMBER     : 13279-22-6
BEILSTEIN REFERENCE NO. : 0123540
REFERENCE               : 5-20-01-00046 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H10-N2-O
MOLECULAR WEIGHT        : 162.21
WISWESSER LINE NOTATION : T3NTJ AVMR
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * N-(Anilinocarbonyl)aziridine
   * 1-Aziridinecarboxanilide
   * N,N-Ethylene-N'-phenylurea
   * N-(Phenylaminocarbonyl)aziridine
   * N-Phenyl-1-aziridinecarboxamide
   * Phenyl-N-carbamoylaziridine
   * 1-Phenylcarbamoylaziridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 21,581,1963
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   29,2184,1969
 
                            *** END OF RECORD ***