*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM7895000
CHEMICAL NAME           : Aziridine, 1,1'-isophthaloylbis(2-methyl-
CAS REGISTRY NUMBER     : 7652-64-4
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C14-H16-N2-O2
MOLECULAR WEIGHT        : 244.32
COMPOUND DESCRIPTOR     : Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Aziridine, 1,1'-(1,3-phenylenedicarbonyl)bis(2-methyl-
   * N,N'-Bispropyleneisophthalamide
   * HX 752
   * 1,1'-(1,3-Phenylenedicarbonyl)bis(2-methylaziridine)
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Severe
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 593 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1500 ng/plate
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 240 mg/kg
REFERENCE :
   WHYHAQ Wuhan Yixueyuan Xuebao.  (China International Book Trading Corp., POB
   2820, Beijing, Peop. Rep. China)  No.1-    1957-    Suspended 1959-76(?). 
   Volume(issue)/page/year: 14(5),1,1985

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***