*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM7970000
CHEMICAL NAME           : 2-Aziridinemethanol, 1-methyl-alpha-phenyl-, (R*,R*)-
CAS REGISTRY NUMBER     : 64889-99-2
LAST UPDATED            : 198405
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H13-N-O
MOLECULAR WEIGHT        : 163.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (R*,R*)-1-Methyl-alpha-phenyl-2-aziridinemethanol
   * N-Methyl phenylhydroxymethyl-2 aziridine R*,R*-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 422 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,149,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,149,1977
 
                            *** END OF RECORD ***