*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM8255000
CHEMICAL NAME           : Aziridine, 1-nonanoyl-
CAS REGISTRY NUMBER     : 63021-51-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H21-N-O
MOLECULAR WEIGHT        : 183.33
WISWESSER LINE NOTATION : T3NTJ AV8
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1-Nonanoylaziridine
   * Nonanoylethyleneimine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 720 mg/kg/20W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Gastrointestinal - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 9,306,1954
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg/20W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 9,306,1954
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 860 mg/kg/27W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Blood - leukemia
   Tumorigenic - tumors at site of application
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 9,306,1954
 
                            *** END OF RECORD ***