*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CM8850000
CHEMICAL NAME : Aziridine, 1-stearoyl-
CAS REGISTRY NUMBER : 3891-30-3
BEILSTEIN REFERENCE NO. : 0187892
REFERENCE : 4-20-00-00016 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H39-N-O
MOLECULAR WEIGHT : 309.60
WISWESSER LINE NOTATION : T3NTJ AV17
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* 1-Stearoylaziridine
* Stearoyl ethyleneimine
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1000 mg/kg/5W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 6,357,1951
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1100 mg/kg/35D-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Endocrine - adrenal cortex tumors
Tumorigenic - tumors at site of application
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 9,306,1954
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 200 mg/kg
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 9,306,1954
*** END OF RECORD ***