*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM9620000
CHEMICAL NAME           : Aziridinium, 1-ethyl-1-(2-hydroxyethyl)-
CAS REGISTRY NUMBER     : 63918-37-6
LAST UPDATED            : 198909
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C6-H14-N-O
MOLECULAR WEIGHT        : 116.21
WISWESSER LINE NOTATION : T3KTJ A2 A2Q
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AF 64A
   * ECMA
   * Ethylcholine mustard aziridinium ion
   * 1-Ethyl-1-(2-hydroxyethyl)aziridinium
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 33810 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   92,349,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 222,140,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 222,140,1982
 
                            *** END OF RECORD ***