*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CN0726000
CHEMICAL NAME           : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,
                          1,1a,2,8,8a,8b-hexahydro-6-amino-1,5-
                          dimethyl-8a-hydroxy-8-(hydroxymethyl)-, 8-carbamate
CAS REGISTRY NUMBER     : 10169-34-3
BEILSTEIN REFERENCE NO. : 4720574
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H18-N4-O5
MOLECULAR WEIGHT        : 334.37
WISWESSER LINE NOTATION : T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KZ L1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Mitomycin D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 36,1461,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAJAAA Journal of Antibiotics, Series A.  (Tokyo, Japan)  V.6-20, 1953-67.
   For publisher information, see JANTAJ.  Volume(issue)/page/year: 20,72,1967
 
                            *** END OF RECORD ***