*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CN0727000
CHEMICAL NAME           : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,
                          1,1a,2,8,8a,8b-hexahydro-6-amino-1,5-
                          dimethyl-8a-hydroxy-8-methylene-,
                          (1aS-(1a-alpha,8a-alpha,8b-alpha))-
CAS REGISTRY NUMBER     : 74148-47-3
BEILSTEIN REFERENCE NO. : 4524448
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H15-N3-O3
MOLECULAR WEIGHT        : 273.32
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Amino-10-decarbamoyloxy-9-dehydro-7-demethoxymitomycin B
   * 9a-O-Demethylmitomycin G
   * Mitomycin Z
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1152,1981
 
                            *** END OF RECORD ***