*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YU9625000
CHEMICAL NAME           : Urs-12-en-28-oic acid, 2-alpha,3-beta,23-trihydroxy-,
                          O-6-deoxy-alpha-L-mannopyranosyl-
                          (1-4)-o-beta-D-glucopyranosyl-(1-6)-o-beta-D-glucopyr
                          anosyl ester
CAS REGISTRY NUMBER     : 16830-15-2
BEILSTEIN REFERENCE NO. : 0078195
REFERENCE               : 4-17-00-03627 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C48-H78-O19
MOLECULAR WEIGHT        : 959.26
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Asiaticoside
   * Blastoestimulina
   * Centelase
   * Dermatologico
   * Madecassol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   32,1463,1972

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 60,1171,1976

 
                            *** END OF RECORD ***