*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YV8588000
CHEMICAL NAME           : Valeronitrile, 4-methyl-
CAS REGISTRY NUMBER     : 542-54-1
BEILSTEIN REFERENCE NO. : 1698246
REFERENCE               : 4-02-00-00946 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C6-H11-N
MOLECULAR WEIGHT        : 97.18
WISWESSER LINE NOTATION : NC2Y1&1
SYNONYMS/TRADE NAMES :
   * Isoamyl cyanide
   * Isoamylkyanid
   * Isocapronitrile
   * Isopentyl cyanide
   * 4-Methylpentanenitrile
   * 4-Methylvaleronitrile
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 488 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEZAAQ Nippon Eiseigaku Zasshi.  Japanese Journal of Hygiene.  (Nippon Eisei
   Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606,
   Japan)  V.1-    1946-  Volume(issue)/page/year: 39,423,1984
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 89 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 5,161,1899
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Cardiac - other changes
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 5,161,1899

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***