*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX3968200
CHEMICAL NAME           : Venom, snail, Conus striatus
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Conus striatus venom
   * C. striatus venom
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   14FHAR "Venomous and Poisonous Animals and Noxious Plants of the Pacific
   Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press
   Inc., 1963  Volume(issue)/page/year: -,83,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   14FHAR "Venomous and Poisonous Animals and Noxious Plants of the Pacific
   Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press
   Inc., 1963  Volume(issue)/page/year: -,83,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 ng/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   14FHAR "Venomous and Poisonous Animals and Noxious Plants of the Pacific
   Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press
   Inc., 1963  Volume(issue)/page/year: -,83,1963
 
                            *** END OF RECORD ***