*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : YX3971200 CHEMICAL NAME : Venom, snake, Aipysurus laevis LAST UPDATED : 199109 DATA ITEMS CITED : 3 COMPOUND DESCRIPTOR : Natural Product SYNONYMS/TRADE NAMES : * Aipysurus laevis venom *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 262 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 14,347,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 155 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 14,347,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 90 ug/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : 35FUAR "Animal, Plant, and Microbial Toxins, Proceedings of the International Symposium, 4th, 1974," Ohsaka, A., et al., eds., 2 vols., New York, Plenum Pub. Corp., 1976 Volume(issue)/page/year: 2,161,1976 *** END OF RECORD ***