*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX3986300
CHEMICAL NAME           : Venom, snake, Hemachatus haemchates
LAST UPDATED            : 199506
DATA ITEMS CITED        : 13
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Hemachatus haemachates venom
   * Hemachatus haemachatus venom
   * H. haemachates venom
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   19DDA6 "Animal Toxins, a Collection of Papers Presented at the International
   Symposium on Animal Toxins, 1st, 1966," Russell, F.E., and P.R. Saunders,
   eds., New York, Pergamon Press Inc., 1967 Volume(issue)/page/year:
   -,283,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2625 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 5,47,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1150 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 208,81,1974
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 1900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 630 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 1250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 1200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30FDAB "Neuropoisons: Their Pathophysiological Actions, 1971-1974," Simpson,
   L.L., and D.R. Curtis, eds., New York, Plenum Pub. Corp., 1974
   Volume(issue)/page/year: 1,21,1971
 
                            *** END OF RECORD ***