*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX3994300
CHEMICAL NAME           : Venom, snake, Pelamis platurus
LAST UPDATED            : 199109
DATA ITEMS CITED        : 8
COMPOUND DESCRIPTOR     : Human
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Pelamis platurus venom
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD25 - Lethal Dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 82 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 21,901,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 92 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 160 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 28,139,1976
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 75 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27UDAK "Food-Drugs from the Sea, Proceedings of the Conference, 3rd,
   Kingston, RI, 1972," Worthen, L.R., ed., Washington, DC, Marine Technology
   Soc., 1973  Volume(issue)/page/year: -,247,1973
 
                            *** END OF RECORD ***