*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZA7072000
CHEMICAL NAME           : Vitallium
CAS REGISTRY NUMBER     : 12629-02-6
OTHER CAS REGISTRY NOS. : 12618-69-8
                          94076-26-3
                          115201-64-4
                          85131-98-2
                          39415-34-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 33
MOLECULAR FORMULA       : C.B.Co.Cr.Fe.Mn.Mo.Ni.Si
MOLECULAR WEIGHT        : 427.28
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Akrit CoMo35
   * AMS 5385D
   * Celsit 290
   * Chromium-cobalt-molybdenum alloy
   * Cobalt-chromium-molybdenum alloy
   * CoCr28Mo
   * CoCr28MoNi
   * DIN 2.4979
   * F 75
   * Haynes stellite 21
   * HS 21
   * KSP-21
   * Milit 21
   * Molybdenum-cobalt-chromium alloy
   * Protasul-2
   * Stellite 21
   * STL21
   * UNS R30021
   * VEW L290
   * Vinertia
   * X25CoCrMo62 28 5
   * Zimaloy
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Musculoskeletal - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   JBSUAK Journal of Bone and Joint Surgery, British Volume.  (10 Shattuck St.,
   Boston, MA 02115) V.30-    1948-  Volume(issue)/page/year: 55,759,1973
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Musculoskeletal - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   16,439,1956

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 10 mg(Mo)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.02 mg(Co)/m3; animal carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.05 mg(Cr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Not classifiable as a human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 52,363,1991

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 52,363,1991

   IARC Cancer Review:Group 2B
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 52,363,1991

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 10 mg(Mo)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,173,1971

   OSHA PEL (Gen Indu):8H TWA 15 mg(Mo)/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Gen Indu):8H TWA 5 mg(Mo)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 15 mg(Mo)/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Construc):8H TWA 5 mg(Mo)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 15 mg(Mo)/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Shipyard):8H TWA 5 mg(Mo)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 15 mg(Mo)/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

   OSHA PEL (Fed Cont):8H TWA 5 mg(Mo)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 10 mg(Mo)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 10 mg(Mo)/m3 JAN 1993
   
   OEL-DENMARK:TWA 10 mg(Mo)/m3 JAN 1993
   
   OEL-FRANCE:TWA 5 mg(Mo)/m3;STEL 10 mg(Mo)/m3 JAN 1993
   
   OEL-GERMANY:TWA 15 mg(Mo)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 10 mg(Mo)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 15 mg(Mo)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 10 mg(Mo)/m3 (total dust) JAN 1993
   
   OEL-SWEDEN:TWA 5 mg(Mo)/m3 (resp. dust) JAN 1993
   
   OEL-SWITZERLAND:TWA 10 mg(Mo)/m3 JAN 1993
   
   OEL-TURKEY:TWA 15 mg(Mo)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 10 mg(Mo)/m3;STEL 20 mg(Mo)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO COBALT METAL, dust and fume-air:10H TWA 0.05 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***