*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZD5703200
CHEMICAL NAME           : Xanthene-9-carboxylic acid, 1-methyl-3-pyrrolidinyl
                          ester, sulfate
CAS REGISTRY NUMBER     : 102585-07-9
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H19-N-O3.H2-O4-S
MOLECULAR WEIGHT        : 407.47
WISWESSER LINE NOTATION : T C666 BO IHJ IVO- CT5NTJ A1 &..H2.S-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AHR 361
   * 1-Methyl-3-pyrrolidinylxanthene-9-carboxylate sulfate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,523,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 205 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,523,1960
 
                            *** END OF RECORD ***