*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZD5706000
CHEMICAL NAME           : 2H-Xantheno(1',2',3':4:5)(1,3)benzodioxino(7,6-g)isoq
                          uinoline-5,14(1H,9H)- dione, 13-amino-
                          3,4,8a,13-tetrahydro-4,15,16-trihydroxy-1-methoxy-12-
                          methyl-, (1R-(1-alpha,4-alpha,8a-beta))-
CAS REGISTRY NUMBER     : 37895-35-5
LAST UPDATED            : 199107
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C27-H24-N2-O9
MOLECULAR WEIGHT        : 520.53
WISWESSER LINE NOTATION : T E6 C666 U6 S66 1A F& FVN OO QO TV D&O&&TTT&&J DQ GZ
                          H1 VQ B&O1 F&Q
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Albofungin
   * Antibiotic P 42-1
   * Antibiotic P42-C
   * Antibiotic P 42-I
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 26,65,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,159,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,162,1981
 
                            *** END OF RECORD ***