*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZH8050000
CHEMICAL NAME           : Zirconium(III) lactate (1:3)
CAS REGISTRY NUMBER     : 63919-14-2
LAST UPDATED            : 199712
DATA ITEMS CITED        : 26
MOLECULAR FORMULA       : C9-H9-O9.H4-O-Zr
MOLECULAR WEIGHT        : 372.44
WISWESSER LINE NOTATION : QY1&VO 3 &-ZR-
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Lactic acid, zirconium salt (3:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 20 ug/kg
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   190,940,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   24,131,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   24,131,1963
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 mg/m3/7H/32W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in pulmonary vascular resistance
   Lungs, Thorax, or Respiration - pleural thickening
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   24,131,1963
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 15 mg/m3/7H/32W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - structural or functional change in trachea
   or bronchi
   Lungs, Thorax, or Respiration - pleural thickening
   Related to Chronic Data - death
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   24,131,1963
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 15 mg/m3/7H/32W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in pulmonary vascular resistance
   Lungs, Thorax, or Respiration - pleural thickening
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   24,131,1963

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 5 mg(Zr)/m3; STEL 10 mg(Zr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Not classifiable as a human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 5 mg(Zr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,285,1971

   OSHA PEL (Gen Indu):8H TWA 5 mg(Zr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 5 mg(Zr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 5 mg(Zr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 5 mg(Zr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 5 mg(Zr)/m3;STEL 10 mg(Zr)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 5 mg(Zr)/m3;STEL 10 mg(Zr)/m3 JAN 1993
   
   OEL-DENMARK:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-FINLAND:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-GERMANY:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-HUNGARY:STEL 5 mg(Zr)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-TURKEY:TWA 5 mg(Zr)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 5 mg(Zr)/m3;STEL 10 mg(Zr)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

 
                            *** END OF RECORD ***