*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CO1747600
CHEMICAL NAME           : 3-Azoniabicyclo(3.2.1)octane,
                          1,3,8,8-tetramethyl-3-(3-(trimethylammonio)propyl)-,
                          dichloride
LAST UPDATED            : 199604
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H36-N2.2Cl
MOLECULAR WEIGHT        : 339.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Dimethylaminopropyl-1-methyl-8,8-dimethyl-3-azobicyclo(3.2.1)octane  
   dimethochloride
   *   1,3,8,8-Tetramethyl-3-(3-(trimethylammonio)propyl)-3-azoniabicyclo(3.2.1
     )octane dichloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 138 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,263,1958
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,263,1958
 
                            *** END OF RECORD ***