*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CN0741000 CHEMICAL NAME : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-1,5-dimethyl-8- (hydroxymethyl)-8a-methoxy-6-isopropoxy-, carbamate CAS REGISTRY NUMBER : 99901-08-3 LAST UPDATED : 198606 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H25-N3-O6 MOLECULAR WEIGHT : 391.47 WISWESSER LINE NOTATION : T D3 C556 EN HN JV MVTTT&J B1OVZ CO1 E1 K1 LOY1&1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 1a,6-Dimethyl-9-(hydroxymethyl)-7-isopropoxymitosane carbamate * 7-i-Propoxy-7-demethoxymitomycin B *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9750 ug/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,804,1980 *** END OF RECORD ***