*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CP8000000
CHEMICAL NAME           : Barbituric acid
CAS REGISTRY NUMBER     : 67-52-7
OTHER CAS REGISTRY NOS. : 32267-40-6
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C4-H4-N2-O3
MOLECULAR WEIGHT        : 128.10
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Hydrouracil, 6-hydroxy-
   * 6-Hydroxyuracil
   * Malonylurea
   * Pyrimidinetriol
   * 2,4,6-Pyrimidinetriol
   * 2,4,6-Pyrimidinetrione
   * 2,4,6(1H,3H,5H)-Pyrimidinetrione
   * 2,4,6-Trihydroxypyrimidine
   * 2,4,6-Trioxohexahydropyrimidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 505 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 106,504,1986

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81718
       No. of Facilities: 28 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 700 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81718
       No. of Facilities: 79 (estimated)
       No. of Industries: 4
       No. of Occupations: 5
       No. of Employees: 3529 (estimated)
       No. of Female Employees: 1481 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***