*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CQ1433500
CHEMICAL NAME           : Barbituric acid, 5-(2-butenyl)-5-isobutyl-2-thio-,
                          sodium salt
CAS REGISTRY NUMBER     : 67050-02-6
LAST UPDATED            : 199107
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H18-N2-O2-S.Na
MOLECULAR WEIGHT        : 277.37
WISWESSER LINE NOTATION : T6VMYNV FHJ CUS F2U2 F1Y1&1 &-NA- &31/6
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(2-Butenyl)-5-isobutyl-2-thiobarbituric acid sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 252 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 34,183,1945
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 114 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 34,183,1945
 
                            *** END OF RECORD ***