*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CQ2100000 CHEMICAL NAME : Barbituric acid, 5-n-butyl-5-ethyl-, sodium salt CAS REGISTRY NUMBER : 35763-44-1 LAST UPDATED : 199009 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C10-H16-N2-O3.Na MOLECULAR WEIGHT : 235.27 WISWESSER LINE NOTATION : T6VMVMV FHJ F4 F2 &-NA- COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Butethal sodium * Butobarbital sodium * Butobarbitione sodium * Neonal sodium * 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-5-ethyl-, monosodium salt * Sodium ethyl n-butyl barbiturate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 197 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,254,1944 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Behavioral - sleep REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 60,323,1937 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 275 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 31,455,1927 *** END OF RECORD ***