*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CQ2310500
CHEMICAL NAME           : Barbituric acid, 5-sec-butyl-5-ethyl-2-thio-, sodium
                          salt
CAS REGISTRY NUMBER     : 947-08-0
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H16-N2-O2-S.Na
MOLECULAR WEIGHT        : 251.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Brevinarcon
   * Brevinarcone
   * 5-sec-Butyl-5-ethyl-2-thiobarbituric acid sodium salt
   * Inactin
   * Inaktin
   * Narkothion
   * 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylpropyl)-2-thioxo-,  
   monosodium salt
   * Thiobutabarbitone sodium
   * Venobarbital
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,719,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   6,407,1961
 
                            *** END OF RECORD ***