*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CN0736000
CHEMICAL NAME           : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,
                          1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-
                          1,5-dimethyl-8-(hydroxymethyl)-, carbamate
CAS REGISTRY NUMBER     : 74985-82-3
BEILSTEIN REFERENCE NO. : 5485913
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H21-N3-O6
MOLECULAR WEIGHT        : 363.41
WISWESSER LINE NOTATION : T D3 B556 BN EN JV MVTTT&J E1 GO1 H1OVZ KO1 L1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9a-O-Methylmitomycin B
   * Mitomycin J
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 36,1461,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 14,103,1971
 
                            *** END OF RECORD ***