*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CQ5500000
CHEMICAL NAME           : Barbituric acid, 5-ethyl-5-isopropyl-, sodium salt
CAS REGISTRY NUMBER     : 143-82-8
LAST UPDATED            : 199107
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H14-N2-O3.Na
MOLECULAR WEIGHT        : 221.24
WISWESSER LINE NOTATION : T6VMVMV FHJ FY1&1 F2 &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Barbituric acid, 5-ethyl-5-isopropyl-, sodium deriv
   * 5-Ethyl-5-isopropylbarbituric acid sodium
   * Ipral sodium
   * Probarbital sodium
   * Probarbitone sodium
   * 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylethyl)-, monosodium  
   salt
   * Sodium 5-ethyl-5-isopropylbarbiturate
   * Sodium probarbital
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 29,509,1940
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 47,2236,1925
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 31,455,1927
 
                            *** END OF RECORD ***