*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CQ7172000
CHEMICAL NAME : Barbituric acid,
5-(1-methylbutyl)-5-(2-(methylthio)ethyl)-2-thio-,
sodium salt
CAS REGISTRY NUMBER : 730-68-7
LAST UPDATED : 199506
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C12-H20-N2-O2-S2.Na
MOLECULAR WEIGHT : 311.45
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Methioturiate
* Methitural sodium
* 5-(1-Methylbutyl)-5-(2-(methylthio)ethyl)-2-thiobarbituric acid sodium
salt
* Neraval
* Sch 3132
* Sodium methiural
* Thiobutal
* Thiogenal
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 75800 ug/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 116,317,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 454 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
STRAAA Strahlentherapie. (Urban & Schwarzenberg, Postfach 202440, D-8000
Munich 2, Fed. Rep. Ger.) V.1- 1912- Volume(issue)/page/year:
127,245,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 99600 ug/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 116,317,1956
*** END OF RECORD ***