*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CU4350000 CHEMICAL NAME : Benz(a)acridine, 8,10,12-trimethyl- CAS REGISTRY NUMBER : 51787-43-0 BEILSTEIN REFERENCE NO. : 0206672 REFERENCE : 4-20-00-04325 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H17-N MOLECULAR WEIGHT : 271.38 WISWESSER LINE NOTATION : T D6 B666 JNJ C1 F1 H1 COMPOUND DESCRIPTOR : Tumorigen SYNONYMS/TRADE NAMES : * 1,3,10-Trimethyl-5,6-benzacridine *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 348 mg/kg/29W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction REFERENCE : ACRSAJ Advances in Cancer Research. (Academic Press, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1953- Volume(issue)/page/year: 4,315,1956 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg/10D-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors REFERENCE : BAFEAG Bulletin de l'Association Francaise pour l'Etude du Cancer. (Paris, France) V.1-52, 1908-65. For publisher information, see BUCABS. Volume(issue)/page/year: 34,22,1947 *** END OF RECORD ***