*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CV4330000
CHEMICAL NAME           : Benzamide, N,N-diethyl-3-ethoxy-4-hydroxy-
CAS REGISTRY NUMBER     : 13898-68-5
BEILSTEIN REFERENCE NO. : 2844455
REFERENCE               : 4-10-00-01483 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C13-H19-N-O3
MOLECULAR WEIGHT        : 237.33
WISWESSER LINE NOTATION : 2N2&VR DQ CO2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Anacardiol
   * DEHB
   * Diethylamide of 3-ethoxy-4-hydroxy-benzoic acid
   * 3-Ethoxy-N,N-diethyl-4-hydroxybenzamide
   * 3-Ethoxy-4-hydroxy-diethylbenzamide
   * 4-Hydroxy-3-ethoxy-benzoic acid diethylamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6900 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RIALA6 Revista do Instituto Adolfo Lutz.  Review of the Adolfo Lutz
   Institute.  (Biblioteca do Instituto Adoilfo Lutz, Caixa Postal, 2027, 01000
   Sao Paulo, Brazil)  V.1-    1941-  Volume(issue)/page/year: 37,75,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 128,176,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 128,176,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5400 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RIALA6 Revista do Instituto Adolfo Lutz.  Review of the Adolfo Lutz
   Institute.  (Biblioteca do Instituto Adoilfo Lutz, Caixa Postal, 2027, 01000
   Sao Paulo, Brazil)  V.1-    1941-  Volume(issue)/page/year: 37,75,1977
 
                            *** END OF RECORD ***