*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CV5571500
CHEMICAL NAME : Benzamide,
4-((methyl-NNO-azoxy)methyl)-N-(1-methylethyl)-
CAS REGISTRY NUMBER : 66944-55-6
OTHER CAS REGISTRY NOS. : 96600-35-0
BEILSTEIN REFERENCE NO. : 5436057
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C12-H17-N3-O2
MOLECULAR WEIGHT : 235.32
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Azoxy 1-procarbazine
* N-Isopropyl-p-methylazoxymethylbenzamide
* N-Isopropyl-alpha-(2-methyl-NNO-azoxy)-p-toluamide
* RO4-8047
* p-Toluamide, N-isopropyl-alpha-(methylazoxy)-
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE : 274 mg/kg
SEX/DURATION : male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,1547,1987
** MUTATION DATA **
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 1 mmol/L
REFERENCE :
CGCYDF Cancer Genetics and Cytogenetics. (Elsevier Science Pub. Co., Inc.,
52 Vanderbilt Ave., New York, NY 10017) V.1- 1979-
Volume(issue)/page/year: 9,25,1983
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - mouse Leukocyte
DOSE/DURATION : 1 mmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
49,127,1989
*** END OF RECORD ***