*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CV8576000
CHEMICAL NAME           : Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro-
CAS REGISTRY NUMBER     : 2277-92-1
BEILSTEIN REFERENCE NO. : 2014120
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C13-H6-Cl5-N-O3
MOLECULAR WEIGHT        : 401.45
WISWESSER LINE NOTATION : QR BG DG FMVR BQ CG EG FG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-
   * 2,2'-Dihydroxy-3,3',5,5',6-pentachlorobenzanilide
   * Diplin
   * ICI 46638
   * Oxyclozanid
   * Oxyclozanide
   * 3,3',5,5',6-Pentachloro-2,2'-dihydroxybenzanilide
   * 3,5,6,3',5'-Pentachloro-2,2'-dihydroxybenzanilide
   * 3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilide
   * Salicylanilide, 3,3',5,5',6-pentachloro-2'-hydroxy-
   * 2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
   * Zanil
   * Zanilox
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 210,744,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Gastrointestinal - hypermotility, diarrhea
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   VETRAX Veterinary Record.  (7 Mansfield St., London W1M 0AT, UK)  V.1- 1888-
    Volume(issue)/page/year: 78,267,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cattle
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   VETRAX Veterinary Record.  (7 Mansfield St., London W1M 0AT, UK)  V.1- 1888-
    Volume(issue)/page/year: 78,267,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VETRAX Veterinary Record.  (7 Mansfield St., London W1M 0AT, UK)  V.1- 1888-
    Volume(issue)/page/year: 78,267,1966
 
                            *** END OF RECORD ***