*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CY1483700
CHEMICAL NAME           : Benzeneacetamide,
                          N-(4-chlorophenyl)-N-(1-(1-methylethyl)-4-piperidinyl
                          )-, monohydrochloride
CAS REGISTRY NUMBER     : 58934-46-6
LAST UPDATED            : 199009
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C22-H27-Cl-N2-O.Cl-H
MOLECULAR WEIGHT        : 407.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(p-Chlorophenyl)-N-(1-isopropylpiperidin-4-yl)phenylacetamide  
   hydrochloride
   * N-(4-Chlorophenyl)-N-(1-(1-methylethyl)-4-piperidinyl)benzeneacetamide  
   hydrochloride
   * Isocainide hydrochloride
   * Lopantrol
   * Lorcainida clorhidrato
   * Lorcainide hydrochloride
   * Lorivox
   * R 15889
   * Remivox
   * Ro 13-1042
   * Socainide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 435 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,12,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,12,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 395 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,12,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,12,1982
 
                            *** END OF RECORD ***